Repeatability of lung function tests during methacholine challenge in wheezy infants

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Repeatability of lung function tests during methacholine challenge in wheezy infants.

BACKGROUND The repeatability of lung function tests and methacholine inhalation tests was evaluated in recurrently wheezy infants over a one month period using the rapid thoracic compression technique. METHODS Eighty-one wheezy, symptom free infants had pairs of methacholine challenge tests performed one month apart. Maximal flow at functional residual capacity (VmaxFRC) and transcutaneous ox...

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Conflicting methacholine challenge tests.

An 11-year-old boy experienced almost daily wheezing, dyspnea on exertion, and sleep perturbation because of cough. In addition, nadir peak expiratory flow (PEF) was below 100 L/min, which was 30% of predicted (328 L/min),1 compatible with severe persistent asthma.2 After the initiation of therapy with 180 g of albuterol 3 times per day, the patient’s domiciliary PEF rose to 200 L/min and his s...

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The effects of inhaled beclomethasone dipropionate on lung function and histamine responsiveness in recurrently wheezy infants.

Inhaled steroids improve pulmonary function and bronchial responsiveness in older asthmatics. Data from studies using subjective outcome measures to determine the effectiveness of inhaled steroids in infants with recurrent wheezing are equivocal. Therefore, this study tested the hypothesis that beclomethasone dipropionate improves pulmonary function, including bronchial responsiveness to histam...

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Lung function response to bronchodilator nebulization via hood in wheezy infants: a pilot study.

BACKGROUND In infants, small volume nebulizers with a face mask are commonly used to facilitate aerosol therapy. However, infants may be disturbed by mask application, causing poor mask-to-face seal and thus reducing the dose delivered. OBJECTIVES To compare lung function response to bronchodilator nebulization via two delivery devices: hood versus mask. METHODS We studied 26 recurrently wh...

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Pulmonary Function and Methacholine Challenge Tests in Patients with Ulcerative Colitis

BACKGROUND Ulcerative colitis is an inflammatory chronic disease which is believed to be a multi organ condition. The prevalence of ulcerative colitis is reportedly increasing in Iran presenting with the same clinical characteristics as in developing countries. Pulmonary manifestations of ulcerative colitis are increasingly reported. In this study, we investigated the incidence of bronchial hyp...

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ژورنال

عنوان ژورنال: Thorax

سال: 1998

ISSN: 0040-6376

DOI: 10.1136/thx.53.11.933